Severe osmotic compression triggers a slowdown of intracellular signaling, which can be explained by molecular crowding
نویسندگان
چکیده
منابع مشابه
Severe osmotic compression triggers a slowdown of intracellular signaling, which can be explained by molecular crowding.
Regulation of the cellular volume is fundamental for cell survival and function. Deviations from equilibrium trigger dedicated signaling and transcriptional responses that mediate water homeostasis and volume recovery. Cells are densely packed with proteins, and molecular crowding may play an important role in cellular processes. Indeed, increasing molecular crowding has been shown to modify th...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2013
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1215367110